| Termijn | Thuis | Uitteam | Uitslag |
|---|---|---|---|
| 13-3-25 18:45 | Athletic Bilbao | AS Rom | 3:1 |
| 13-3-25 18:45 | Lazio Rom | Viktoria Pilsen | 1:1 |
| 13-3-25 18:45 | Olympiakos Piräus | FK Bodö/Glimt | 2:1 |
| 13-3-25 18:45 | Eintracht Frankfurt | Ajax Amsterdam | 4:1 |
| 13-3-25 21:00 | Tottenham Hotspur | AZ Alkmaar | 3:1 |
| 13-3-25 21:00 | Manchester United | Real Sociedad | 4:1 |
| 13-3-25 21:00 | Olympique Lyon | FCSB Bukarest | 4:0 |
| 13-3-25 21:00 | Glasgow Rangers | Fenerbahce Istanbul | 3:4n.p. |